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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2A
All Species:
39.7
Human Site:
Y318
Identified Species:
72.78
UniProt:
Q9BTU6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTU6
NP_060895.1
479
54022
Y318
N
D
N
W
L
I
K
Y
D
C
P
M
D
S
S
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
Y318
N
D
N
W
L
I
K
Y
D
S
S
Y
C
T
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
Y323
N
D
N
W
L
I
K
Y
D
C
P
M
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q2TBE6
479
54239
Y318
N
D
N
W
L
I
K
Y
D
C
P
M
D
N
S
Rat
Rattus norvegicus
Q99M64
478
54286
Y317
N
D
N
W
L
I
K
Y
D
Y
P
M
D
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
Y242
N
D
N
W
L
V
R
Y
E
K
Q
S
D
G
S
Chicken
Gallus gallus
Q5ZIK0
479
53903
Y312
N
D
N
W
L
V
R
Y
E
K
Q
D
D
G
L
Frog
Xenopus laevis
Q08B31
469
53187
Y309
N
D
N
W
L
I
K
Y
D
C
P
M
D
S
A
Zebra Danio
Brachydanio rerio
Q6PE18
447
51424
Y286
N
D
N
W
L
I
K
Y
D
Y
P
M
D
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
Y309
N
E
N
W
L
I
K
Y
D
N
S
K
G
K
N
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
Y321
S
D
N
W
L
I
K
Y
I
L
A
D
V
I
D
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
Y332
N
D
N
W
L
I
K
Y
E
K
T
T
M
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
L397
L
D
N
W
M
V
K
L
I
K
L
S
N
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
97.5
N.A.
95.4
94.9
N.A.
59.7
60.1
78
76.6
N.A.
N.A.
55.5
40.2
52.3
Protein Similarity:
100
98.3
N.A.
98.1
N.A.
97.6
96.8
N.A.
70.3
72.4
83.9
83.7
N.A.
N.A.
69.9
50.2
66.8
P-Site Identity:
100
66.6
N.A.
100
N.A.
93.3
80
N.A.
53.3
46.6
93.3
86.6
N.A.
N.A.
53.3
46.6
53.3
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
86.6
N.A.
73.3
66.6
100
93.3
N.A.
N.A.
66.6
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
31
0
0
8
0
0
% C
% Asp:
0
93
0
0
0
0
0
0
62
0
0
16
62
0
8
% D
% Glu:
0
8
0
0
0
0
0
0
24
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
77
0
0
16
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
85
0
0
31
0
8
0
8
8
% K
% Leu:
8
0
0
0
93
0
0
8
0
8
8
0
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
47
8
0
0
% M
% Asn:
85
0
100
0
0
0
0
0
0
8
0
0
8
24
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
8
16
16
0
24
47
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
8
0
16
0
% T
% Val:
0
0
0
0
0
24
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
16
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _